Info
| ID | 3518 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C6 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(NC(=S)Nc1ccc(C(F)(F)F)cc1)c1ccco1.[Cl-].[Cl-] |
TUCAN
C23Cl2F3N2O2RuS/(1-15)(2-14)(3-14)(4-5)(4-16)(5-15)(6-12)(6-17)(7-10)(7-15)(8-9)(8-19)(9-20)(10-16)(11-13)(11-17)(12-18)(13-18)(14-16)(17-22)(18-25)(19-27)(20-21)(20-27)(21-24)(21-26)(22-28)(22-29)(22-30)(23-24)(23-25)(23-31)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 18 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 31 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 35 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 50 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 53 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.2e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»