Info
| ID | 3516 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C4 |
| SMILES | CCc1cccc(CC)c1NC(=S)NC(=O)c1ccco1.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C26Cl2N2O2RuS/(1-12)(2-19)(3-20)(4-19)(5-15)(6-8)(6-14)(7-13)(7-23)(8-17)(9-11)(9-18)(10-16)(10-18)(11-20)(12-17)(13-24)(14-21)(15-21)(16-20)(17-22)(18-19)(21-22)(22-28)(23-30)(24-25)(24-30)(25-27)(25-29)(26-27)(26-28)(26-31)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 14 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 19 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 23 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 25 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 28 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 96 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»