Info
| ID | 3515 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C3 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(NC(=S)NCCc1ccccc1)c1ccco1.[Cl-].[Cl-] |
TUCAN
C24Cl2N2O2RuS/(1-17)(2-16)(3-17)(4-18)(4-20)(5-10)(5-16)(6-15)(6-22)(7-8)(7-13)(8-9)(9-18)(10-19)(11-12)(11-16)(12-19)(13-14)(14-18)(15-21)(17-19)(20-25)(21-28)(22-23)(22-28)(23-26)(23-27)(24-25)(24-26)(24-29)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 15 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 27 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 32 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 44 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 54 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.2e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»