Info
| ID | 3514 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C2 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(NC(=S)NCc1ccccc1)c1ccco1.[Cl-].[Cl-] |
TUCAN
C23Cl2N2O2RuS/(1-16)(2-15)(3-16)(4-9)(4-18)(5-14)(5-21)(6-7)(6-12)(7-8)(8-17)(9-15)(10-11)(10-18)(11-15)(12-13)(13-17)(14-20)(16-18)(17-19)(19-24)(20-27)(21-22)(21-27)(22-25)(22-26)(23-24)(23-25)(23-28)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 20 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 28 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 33 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 42 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 47 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.2e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»