Info
| ID | 3513 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | C1 |
| SMILES | Cc1ccc(C(C)C)cc1.O=C(NC(=S)Nc1ccccc1)c1ccco1.[Cl-].[Cl-] |
TUCAN
C22Cl2N2O2RuS/(1-16)(2-15)(3-16)(4-9)(4-17)(5-14)(5-20)(6-7)(6-12)(7-8)(8-18)(9-15)(10-11)(10-17)(11-15)(12-13)(13-18)(14-19)(16-17)(18-23)(19-26)(20-21)(20-26)(21-24)(21-25)(22-23)(22-24)(22-27)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| IMR-32 | 15 | — | 10.1002/chem.202004954 | 2021 |
| HeLa | 23 | — | 10.1002/chem.202004954 | 2021 |
| HepG2 | 26 | — | 10.1002/chem.202004954 | 2021 |
| A431 | 28 | — | 10.1002/chem.202004954 | 2021 |
| SW40 | 31 | — | 10.1002/chem.202004954 | 2021 |
| Vero | 1.1e+02 | — | 10.1002/chem.202004954 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«They also promoted cell death by apoptosis and cell cycle arrest.»