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Complex #3423 — Ru(2) [Ru-sq]

2D Structure

Structure
⬇ MOL V3000

Info

ID3423
MetalRu
Oxidation state2
Charge1
Donor atoms{"O": 1, "N": 4}
AbbreviationRu-sq
SMILESO=C1C=CC=CC1[O-].c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1

TUCAN

C54H37N4O2Ru/(1-44)(2-40)(3-43)(4-50)(5-38)(6-46)(7-91)(8-47)(9-39)(10-45)(11-82)(12-52)(13-58)(14-41)(15-42)(16-59)(17-55)(18-49)(19-56)(20-66)(21-51)(22-54)(23-67)(24-53)(25-57)(26-61)(27-62)(28-64)(29-83)(30-60)(31-65)(32-63)(33-48)(34-68)(35-84)(36-69)(37-85)(38-40)(38-43)(39-46)(39-47)(40-44)(41-56)(41-57)(42-49)(42-70)(43-50)(44-72)(45-71)(45-82)(46-52)(47-58)(48-61)(48-68)(49-73)(50-72)(51-54)(51-67)(52-76)(53-64)(53-74)(54-90)(55-75)(55-83)(56-59)(57-62)(58-76)(59-78)(60-77)(60-84)(61-65)(62-78)(63-80)(63-85)(64-79)(65-81)(66-67)(66-91)(68-69)(69-81)(70-71)(70-86)(71-72)(73-75)(73-87)(74-77)(74-88)(75-76)(77-78)(79-80)(79-89)(80-81)(82-92)(83-93)(84-94)(85-95)(86-87)(86-92)(87-93)(88-89)(88-94)(89-95)(90-91)(90-97)(91-96)(92-98)(93-98)(94-98)(95-98)

Measurements (8)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A2780cisR0.45— 10.1021/acs.jmedchem.0c00431 2020
HeLa0.5— 10.1021/acs.jmedchem.0c00431 2020
A27800.67— 10.1021/acs.jmedchem.0c00431 2020
RPE-10.9— 10.1021/acs.jmedchem.0c00431 2020
MRC-50.95— 10.1021/acs.jmedchem.0c00431 2020
CT-261— 10.1021/acs.jmedchem.0c00431 2020
CT-26 LUC1.5— 10.1021/acs.jmedchem.0c00431 2020
A2780/ADR4.1— 10.1021/acs.jmedchem.0c00431 2020