Info
| ID | 3396 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"P": 1} |
| Abbreviation | 1 |
| SMILES | CP(C)c1ccc2ccc3cccc4ccc1c2c34.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C28Cl2PRu/(1-17)(2-17)(3-18)(4-11)(4-23)(5-12)(5-22)(6-9)(6-22)(7-9)(7-19)(8-13)(8-21)(10-16)(10-23)(11-18)(12-25)(13-28)(14-15)(14-19)(15-21)(16-18)(17-23)(19-20)(20-22)(20-24)(21-24)(24-25)(25-28)(26-29)(27-29)(28-29)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| SW620 | 6.5 | — | 10.1021/acs.inorgchem.8b02541 | 2018 |
| MCF-10A | 6.9 | — | 10.1021/acs.inorgchem.8b02541 | 2018 |
| A375 | 9 | — | 10.1021/acs.inorgchem.8b02541 | 2018 |
| MCF-7 | 9.7 | — | 10.1021/acs.inorgchem.8b02541 | 2018 |
| A549 | 17 | — | 10.1021/acs.inorgchem.8b02541 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complexes 1−6 are all capable of inducing apoptosis, but with various degrees of magnitude.»