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Complex #3251 — Ru(2) [9]

2D Structure

Structure
⬇ MOL V3000

Info

ID3251
MetalRu
Oxidation state2
Charge2
Donor atoms{"N": 6}
Abbreviation9
SMILESc1ccc2sc(-c3nccc4c3[nH]c3ccccc34)nc2c1.c1cnc2c(ccc3nccnc32)n1.c1cnc2c(ccc3nccnc32)n1

TUCAN

C38H23N11RuS/(1-41)(2-35)(3-46)(4-24)(5-31)(6-47)(7-39)(8-27)(9-26)(10-28)(11-44)(12-29)(13-25)(14-40)(15-33)(16-42)(17-30)(18-43)(19-45)(20-36)(21-32)(22-34)(23-66)(24-25)(24-48)(25-49)(26-28)(26-60)(27-33)(27-38)(28-29)(29-32)(30-34)(30-56)(31-36)(31-57)(32-58)(33-36)(34-52)(35-37)(35-41)(37-38)(37-53)(38-57)(39-46)(39-68)(40-42)(40-67)(41-69)(42-62)(43-45)(43-71)(44-47)(44-72)(45-65)(46-63)(47-64)(48-50)(48-68)(49-51)(49-62)(50-51)(50-63)(51-67)(52-54)(52-65)(53-59)(53-66)(54-55)(54-71)(55-56)(55-64)(56-72)(57-66)(58-60)(58-70)(59-61)(59-69)(60-73)(61-70)(61-73)(67-74)(68-74)(69-74)(70-74)(71-74)(72-74)

Measurements (1)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
PC-3493 10.1016/j.ejmech.2024.116618 2024

🧬 Cell Death Types (1)

Apoptosis high
«Upon photoactivation, they generate ROS, leading to mitochondrial dysfunction and lysosomal damage and ultimately cell apoptosis.»