Info
| ID | 3250 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | 8 |
| SMILES | Cc1csc(-c2nccc3c2[nH]c2ccccc23)n1.c1cnc2c(ccc3nccnc32)n1.c1cnc2c(ccc3nccnc32)n1 |
TUCAN
C35H23N11RuS/(1-44)(2-42)(3-25)(4-33)(5-43)(6-36)(7-30)(8-29)(9-39)(10-24)(11-57)(12-26)(13-38)(14-27)(15-37)(16-28)(17-24)(18-40)(19-41)(20-31)(21-32)(22-24)(23-63)(24-50)(25-26)(25-46)(26-45)(27-31)(27-35)(28-32)(28-54)(29-33)(29-55)(30-34)(30-44)(31-33)(32-47)(34-35)(34-56)(35-55)(36-42)(36-66)(37-38)(37-59)(38-65)(39-43)(39-69)(40-41)(40-68)(41-62)(42-60)(43-61)(44-64)(45-49)(45-59)(46-48)(46-66)(47-52)(47-62)(48-49)(48-60)(49-65)(50-57)(50-67)(51-56)(51-58)(51-64)(52-53)(52-68)(53-54)(53-61)(54-69)(55-63)(56-63)(57-70)(58-67)(58-70)(64-71)(65-71)(66-71)(67-71)(68-71)(69-71)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PC-3 | 60 | 8.5 | 10.1016/j.ejmech.2024.116618 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Upon photoactivation, they generate ROS, leading to mitochondrial dysfunction and lysosomal damage and ultimately cell apoptosis.»