Info
| ID | 3246 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 7} |
| Abbreviation | 4 |
| SMILES | c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1.c1ccc2c(c1)[nH]c1c(-c3nccs3)nccc12 |
TUCAN
C34H25N7RuS/(1-28)(2-32)(3-49)(4-34)(5-35)(6-46)(7-38)(8-47)(9-48)(10-29)(11-36)(12-31)(13-41)(14-40)(15-30)(16-50)(17-33)(18-26)(19-27)(20-45)(21-37)(22-58)(23-42)(24-39)(25-60)(26-27)(26-36)(27-31)(28-34)(28-52)(29-34)(29-46)(30-38)(30-47)(31-53)(32-38)(32-54)(33-40)(33-48)(35-40)(35-56)(36-44)(37-43)(37-45)(39-42)(39-50)(41-42)(41-57)(43-44)(43-51)(44-53)(45-62)(46-61)(47-63)(48-64)(49-58)(49-66)(50-65)(51-55)(51-60)(52-54)(52-61)(53-60)(54-63)(55-59)(55-62)(56-57)(56-64)(57-65)(58-67)(59-66)(59-67)(61-68)(62-68)(63-68)(64-68)(65-68)(66-68)(67-68)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PC-3 | 37 | 2.6 | 10.1016/j.ejmech.2024.116618 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Upon photoactivation, they generate ROS, leading to mitochondrial dysfunction and lysosomal damage and ultimately cell apoptosis.»