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Complex #3176 — Ru(2) [Ru2]

2D Structure

Structure
⬇ MOL V3000

Info

ID3176
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 7}
AbbreviationRu2
SMILES[c-]1cccc2c1c1ncccc1c1nc3ccc(-c4ccc5ccc6cccc7ccc4c5c67)cc3nc21.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

TUCAN

C55H34N7Ru/(1-55)(2-40)(3-37)(4-41)(5-76)(6-46)(7-77)(8-51)(9-78)(10-45)(11-57)(12-62)(13-54)(14-43)(15-50)(16-48)(17-47)(18-61)(19-56)(20-38)(21-52)(22-53)(23-39)(24-79)(25-63)(26-36)(27-59)(28-80)(29-64)(30-49)(31-42)(32-44)(33-58)(34-60)(35-42)(35-68)(36-65)(36-81)(37-40)(37-41)(38-51)(38-52)(39-53)(39-57)(40-76)(41-83)(42-49)(43-50)(43-65)(44-64)(44-67)(45-62)(45-69)(46-55)(46-67)(47-48)(47-66)(48-79)(49-63)(50-84)(51-77)(52-86)(53-87)(54-61)(54-69)(55-56)(56-73)(57-78)(58-60)(58-89)(59-60)(59-80)(61-74)(62-73)(63-72)(64-75)(65-74)(66-85)(66-88)(67-71)(68-72)(68-88)(69-70)(70-71)(70-75)(71-73)(72-82)(74-75)(76-91)(77-92)(78-95)(79-94)(80-96)(81-84)(81-90)(82-85)(82-90)(83-86)(83-91)(84-93)(85-93)(86-92)(87-89)(87-95)(88-94)(89-96)(91-97)(92-97)(93-97)(94-97)(95-97)(96-97)

Measurements (2)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A549118.3 10.1002/chem.202003031 2020
MCF-71512 10.1002/chem.202003031 2020

🧬 Cell Death Types (1)

Apoptosis high
«This result also indicates that apoptosis, especially late apoptosis is the dominant cell death pathway.»