Info
| ID | 3067 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 5} |
| Abbreviation | 2 |
| SMILES | CN(C)C(=N)NC(=N)N.[Cl-].c1ccccc1 |
TUCAN
C10H17N5Ru/(1-18)(2-19)(3-20)(4-21)(5-22)(6-23)(7-24)(8-24)(9-24)(10-25)(11-25)(12-25)(13-29)(14-32)(15-28)(16-31)(17-28)(18-19)(18-20)(19-21)(20-22)(21-23)(22-23)(24-30)(25-30)(26-28)(26-29)(26-31)(27-29)(27-30)(27-32)(31-33)(32-33)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 21 | — | 10.1039/c7ra06514k | 2017 |
| A2780 | 24 | — | 10.1039/c7ra06514k | 2017 |
| A549 | 29 | — | 10.1039/c7ra06514k | 2017 |
| HEK293 | — | — | 10.1039/c7ra06514k | 2017 |
🧬 Cell Death Types (1)
Apoptosis
high
«All of these morphological changes observed for 1 and 2, suggest that the cells are committed to both apoptotic and necrotic mode of cell death in a time-dependent manner. In particular, the observed ...»