Info
| ID | 3066 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 5} |
| Abbreviation | 1 |
| SMILES | CN(C)C(=N)NC(=N)N.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C14H25N5Ru/(1-27)(2-27)(3-35)(4-27)(5-29)(6-28)(7-28)(8-30)(9-28)(10-36)(11-26)(12-26)(13-31)(14-32)(15-26)(16-36)(17-36)(18-37)(19-37)(20-37)(21-40)(22-40)(23-43)(24-41)(25-44)(26-34)(27-35)(28-35)(29-30)(29-34)(30-33)(31-32)(31-34)(32-33)(33-35)(36-42)(37-42)(38-40)(38-41)(38-43)(39-41)(39-42)(39-44)(43-45)(44-45)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 7.9 | — | 10.1039/c7ra06514k | 2017 |
| A549 | 16 | — | 10.1039/c7ra06514k | 2017 |
| A2780 | 16 | — | 10.1039/c7ra06514k | 2017 |
| HEK293 | — | — | 10.1039/c7ra06514k | 2017 |
🧬 Cell Death Types (1)
Apoptosis
high
«All of these morphological changes observed for 1 and 2, suggest that the cells are committed to both apoptotic and necrotic mode of cell death in a time-dependent manner. In particular, the observed ...»