Info
| ID | 306 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"O": 1, "N": 2, "P": 2} |
| Abbreviation | Ru(GAC) |
| SMILES | O=C([O-])c1cc(O)c(O)c(O)c1.c1ccc(-c2ccccn2)nc1.c1ccc(P(CCCCP(c2ccccc2)c2ccccc2)c2ccccc2)cc1 |
TUCAN
C45H41N2O5P2Ru/(1-45)(2-49)(3-42)(4-81)(5-81)(6-50)(7-44)(8-48)(9-82)(10-47)(11-70)(12-70)(13-71)(14-56)(15-53)(16-71)(17-52)(18-43)(19-46)(20-57)(21-55)(22-60)(23-61)(24-82)(25-54)(26-58)(27-59)(28-62)(29-64)(30-63)(31-65)(32-73)(33-67)(34-66)(35-51)(36-74)(37-69)(38-68)(39-92)(40-91)(41-93)(42-45)(42-83)(43-46)(43-75)(44-49)(44-83)(45-47)(46-51)(47-49)(48-50)(48-84)(50-55)(51-73)(52-72)(52-77)(53-56)(53-84)(54-57)(54-85)(55-56)(57-58)(58-60)(59-60)(59-85)(61-62)(61-65)(62-86)(63-64)(63-65)(64-86)(66-67)(66-69)(67-76)(68-72)(68-78)(69-74)(70-71)(70-81)(71-82)(72-80)(73-87)(74-88)(75-76)(75-87)(76-88)(77-79)(77-92)(78-79)(78-93)(79-91)(80-89)(80-90)(81-94)(82-95)(83-94)(84-94)(85-95)(86-95)(87-96)(88-96)(91-96)(92-96)(93-96)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 6.8 | — | 10.1039/d0dt03490h | 2020 |
| MCF-7 | 11 | — | 10.1039/d0dt03490h | 2020 |
| L-929 | 18 | — | 10.1039/d0dt03490h | 2020 |
| MCF-10A | 25 | — | 10.1039/d0dt03490h | 2020 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.