Info
| ID | 3024 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | 2 |
| SMILES | Nc1ccc(-c2ccc3nc4c5cccnc5c5ncccc5c4nc3c2)cc1N.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C44H32N10Ru/(1-59)(2-51)(3-42)(4-60)(5-64)(6-33)(7-61)(8-35)(9-38)(10-46)(11-63)(12-36)(13-62)(14-41)(15-44)(16-43)(17-34)(18-40)(19-39)(20-47)(21-52)(22-49)(23-50)(24-45)(25-54)(26-37)(27-48)(28-53)(29-77)(30-78)(31-78)(32-77)(33-36)(33-59)(34-36)(34-67)(35-47)(35-60)(37-40)(37-68)(38-40)(38-61)(39-54)(39-62)(41-44)(41-66)(42-51)(42-63)(43-55)(43-65)(44-56)(45-46)(45-57)(46-64)(47-48)(48-71)(49-50)(49-55)(50-74)(51-58)(52-56)(52-70)(53-54)(53-72)(55-56)(57-69)(57-76)(58-73)(58-75)(59-81)(60-82)(61-83)(62-84)(63-85)(64-79)(65-74)(65-77)(66-70)(66-86)(67-68)(67-81)(68-83)(69-75)(69-79)(70-80)(71-72)(71-82)(72-84)(73-76)(73-86)(74-78)(75-85)(76-80)(81-87)(82-87)(83-87)(84-87)(85-87)(86-87)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 14 | — | 10.1039/c2dt12402e | 2012 |
| HepG2 | 15 | — | 10.1039/c2dt12402e | 2012 |
🧬 Cell Death Types (1)
Apoptosis
high
«the majority of the HepG2 cells treated with either complex 1 or 2 displayed the classic morphological features of apoptosis after exposure to 20 μM of the complexes, including nuclear condensation, c...»