Info
| ID | 301 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 2 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[O-]c1ccc2ccccc2c1C=Nc1cnc2ccccc2c1 |
TUCAN
C30H27N2ORu/(1-31)(2-39)(3-34)(4-29)(5-29)(6-33)(7-37)(8-40)(9-45)(10-38)(11-41)(12-36)(13-42)(14-53)(15-43)(16-54)(17-32)(18-44)(19-29)(20-52)(21-28)(22-30)(23-30)(24-28)(25-28)(26-30)(27-35)(28-49)(29-52)(30-52)(31-45)(31-47)(32-38)(32-47)(33-34)(33-49)(34-50)(35-44)(35-50)(36-43)(36-46)(37-46)(37-56)(38-39)(39-41)(40-42)(40-43)(41-51)(42-55)(44-49)(45-57)(46-55)(47-51)(48-51)(48-53)(48-57)(50-52)(53-59)(54-56)(54-58)(55-58)(56-59)(57-60)(58-61)(59-61)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| LN229 | 22 | — | 10.1039/d0dt02167a | 2020 |
| L-929 | 44 | — | 10.1039/d0dt02167a | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«The studied compound lead to apoptosis of GB cells as evidenced by nuclear condensation, blebbing, and enhanced caspase 3/7 activity.»