Info
| ID | 3009 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 8} |
| Abbreviation | 6 |
| SMILES | O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.c1ccc(-c2cc(-c3ccccn3)nc(-c3ccccn3)c2)nc1.c1ccc2n[nH]cc2c1 |
TUCAN
C41H28N8O6RuS2/(1-30)(2-29)(3-41)(4-33)(5-50)(6-32)(7-56)(8-48)(9-44)(10-58)(11-31)(12-49)(13-57)(14-43)(15-39)(16-40)(17-36)(18-37)(19-59)(20-34)(21-35)(22-51)(23-46)(24-47)(25-45)(26-38)(27-42)(28-72)(29-44)(29-54)(30-32)(30-58)(31-34)(31-51)(32-38)(33-52)(33-65)(34-68)(35-50)(35-53)(36-43)(36-60)(37-42)(37-59)(38-64)(39-42)(39-61)(40-43)(40-57)(41-48)(41-63)(44-48)(45-51)(45-55)(46-47)(46-50)(47-69)(49-52)(49-62)(52-61)(53-66)(53-69)(54-56)(54-63)(55-67)(55-68)(56-72)(57-74)(58-71)(59-70)(60-62)(60-74)(61-70)(62-73)(63-75)(64-65)(64-71)(65-73)(66-76)(66-78)(67-77)(67-79)(68-84)(69-85)(72-75)(73-86)(74-86)(75-86)(76-85)(76-86)(77-84)(77-86)(80-84)(81-84)(82-85)(83-85)(84-86)(85-86)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 27 | — | 10.1039/d2dt02203f | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The mechanistic studies revealed that the complexes induce apoptosis and generate reactive oxygen species (ROS) upon green light (λex = 530 nm) irradiation.»