Info
| ID | 3008 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 7} |
| Abbreviation | 5 |
| SMILES | O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.c1ccc(-c2cc(-c3cccs3)cc(-c3ccccn3)n2)nc1.c1ccc2n[nH]cc2c1 |
TUCAN
C40H27N7O6RuS3/(1-38)(2-33)(3-42)(4-41)(5-55)(6-44)(7-64)(8-54)(9-45)(10-46)(11-31)(12-32)(13-35)(14-30)(15-28)(16-34)(17-37)(18-29)(19-40)(20-56)(21-49)(22-36)(23-48)(24-43)(25-39)(26-47)(27-69)(28-34)(28-46)(29-35)(29-61)(30-51)(30-57)(31-44)(31-65)(32-36)(32-52)(33-45)(33-50)(34-58)(35-40)(36-49)(37-39)(37-66)(38-51)(38-59)(39-64)(40-56)(41-42)(41-45)(42-60)(43-44)(43-47)(46-55)(47-53)(48-49)(48-67)(50-54)(50-60)(51-66)(52-62)(52-67)(53-63)(53-65)(54-69)(55-71)(56-68)(57-61)(57-70)(58-59)(58-71)(59-70)(60-72)(61-68)(62-73)(62-75)(63-74)(63-76)(64-81)(65-82)(66-81)(67-83)(69-72)(70-84)(71-84)(72-84)(73-83)(73-84)(74-82)(74-84)(77-82)(78-82)(79-83)(80-83)(82-84)(83-84)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 1.9e+02 | — | 10.1039/d2dt02203f | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The mechanistic studies revealed that the complexes induce apoptosis and generate reactive oxygen species (ROS) upon green light (λex = 530 nm) irradiation.»