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Complex #3007 — Ru(2) [4]

2D Structure

Structure
⬇ MOL V3000

Info

ID3007
MetalRu
Oxidation state2
Charge0
Donor atoms{"N": 7}
Abbreviation4
SMILESO=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.c1ccc(-c2cc(-c3ccco3)cc(-c3ccccn3)n2)nc1.c1ccc2n[nH]cc2c1

TUCAN

C40H27N7O7RuS2/(1-28)(2-37)(3-42)(4-55)(5-44)(6-33)(7-54)(8-41)(9-45)(10-46)(11-31)(12-32)(13-34)(14-30)(15-38)(16-62)(17-36)(18-29)(19-40)(20-56)(21-49)(22-35)(23-48)(24-43)(25-39)(26-47)(27-69)(28-33)(28-46)(29-34)(29-61)(30-51)(30-57)(31-44)(31-66)(32-35)(32-52)(33-58)(34-40)(35-49)(36-39)(36-63)(37-45)(37-50)(38-51)(38-59)(39-62)(40-56)(41-42)(41-45)(42-60)(43-44)(43-47)(46-55)(47-53)(48-49)(48-67)(50-54)(50-60)(51-63)(52-64)(52-67)(53-65)(53-66)(54-69)(55-71)(56-68)(57-61)(57-70)(58-59)(58-71)(59-70)(60-72)(61-68)(62-77)(63-77)(64-73)(64-75)(65-74)(65-76)(66-82)(67-83)(69-72)(70-84)(71-84)(72-84)(73-83)(73-84)(74-82)(74-84)(78-82)(79-82)(80-83)(81-83)(82-84)(83-84)

Measurements (1)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
MCF-71.9e+02 10.1039/d2dt02203f 2022

🧬 Cell Death Types (1)

Apoptosis high
«The mechanistic studies revealed that the complexes induce apoptosis and generate reactive oxygen species (ROS) upon green light (λex = 530 nm) irradiation.»