Info
| ID | 3006 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 8} |
| Abbreviation | 3 |
| SMILES | O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.c1ccc(-c2cc(-c3ccccn3)nc(-c3ccccn3)c2)nc1.c1cn[nH]c1 |
TUCAN
C37H26N8O6RuS2/(1-37)(2-51)(3-50)(4-27)(5-39)(6-36)(7-53)(8-35)(9-32)(10-34)(11-29)(12-28)(13-41)(14-38)(15-54)(16-33)(17-31)(18-30)(19-52)(20-45)(21-43)(22-46)(23-44)(24-40)(25-42)(26-66)(27-50)(27-51)(28-33)(28-53)(29-33)(29-56)(30-40)(30-55)(31-34)(31-41)(32-41)(32-47)(34-62)(35-37)(35-39)(36-48)(36-59)(37-57)(38-40)(38-54)(39-52)(42-45)(42-63)(43-46)(43-49)(44-48)(44-58)(45-46)(47-60)(47-62)(48-56)(49-61)(49-63)(50-69)(51-66)(52-68)(53-64)(54-65)(55-58)(55-65)(56-64)(57-59)(57-68)(58-67)(59-67)(60-70)(60-72)(61-71)(61-73)(62-78)(63-79)(66-69)(67-80)(68-80)(69-80)(70-78)(70-80)(71-79)(71-80)(74-78)(75-78)(76-79)(77-79)(78-80)(79-80)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 2.2e+02 | — | 10.1039/d2dt02203f | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The mechanistic studies revealed that the complexes induce apoptosis and generate reactive oxygen species (ROS) upon green light (λex = 530 nm) irradiation.»