Info
| ID | 3004 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 7} |
| Abbreviation | 1 |
| SMILES | O=C1[N-]S(=O)(=O)c2ccccc21.O=C1[N-]S(=O)(=O)c2ccccc21.c1ccc(-c2cc(-c3ccco3)cc(-c3ccccn3)n2)nc1.c1cn[nH]c1 |
TUCAN
C36H25N7O7RuS2/(1-35)(2-50)(3-49)(4-48)(5-29)(6-33)(7-30)(8-36)(9-51)(10-34)(11-39)(12-26)(13-31)(14-27)(15-28)(16-38)(17-42)(18-56)(19-44)(20-43)(21-41)(22-40)(23-37)(24-32)(25-63)(26-30)(26-45)(27-31)(27-50)(28-39)(28-60)(29-48)(29-49)(30-44)(31-36)(32-46)(32-53)(33-34)(33-56)(34-57)(35-46)(35-54)(36-55)(37-42)(37-51)(38-42)(38-52)(39-41)(40-44)(40-61)(41-43)(43-47)(45-58)(45-61)(46-57)(47-59)(47-60)(48-66)(49-63)(50-62)(51-64)(52-53)(52-64)(53-65)(54-55)(54-65)(55-62)(56-71)(57-71)(58-67)(58-69)(59-68)(59-70)(60-76)(61-77)(63-66)(64-78)(65-78)(66-78)(67-77)(67-78)(68-76)(68-78)(72-76)(73-76)(74-77)(75-77)(76-78)(77-78)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 1.1e+02 | — | 10.1039/d2dt02203f | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The mechanistic studies revealed that the complexes induce apoptosis and generate reactive oxygen species (ROS) upon green light (λex = 530 nm) irradiation.»