Info
| ID | 300 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 1 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[O-]c1ccccc1C=Nc1cnc2ccccc2c1 |
TUCAN
C26H25N2ORu/(1-39)(2-33)(3-27)(4-34)(5-46)(6-32)(7-29)(8-38)(9-30)(10-36)(11-35)(12-37)(13-48)(14-40)(15-47)(16-31)(17-27)(18-26)(19-26)(20-27)(21-41)(22-28)(23-26)(24-28)(25-28)(26-43)(27-46)(28-46)(29-42)(29-49)(30-31)(30-39)(31-51)(32-33)(32-43)(33-44)(34-41)(34-44)(35-40)(35-42)(36-39)(36-45)(37-38)(37-50)(38-40)(41-43)(42-50)(44-46)(45-48)(45-51)(47-49)(47-52)(48-53)(49-53)(50-52)(51-54)(52-55)(53-55)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| LN229 | 23 | — | 10.1039/d0dt02167a | 2020 |
| L-929 | 68 | — | 10.1039/d0dt02167a | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«The studied compound lead to apoptosis of GB cells as evidenced by nuclear condensation, blebbing, and enhanced caspase 3/7 activity.»