Info
| ID | 2945 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1} |
| Abbreviation | 8 |
| SMILES | COC(=O)c1cccc(/N=C/c2ccc3ccccc3c2[O-])c1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C29H28NO3Ru/(1-29)(2-32)(3-29)(4-33)(5-38)(6-44)(7-29)(8-31)(9-52)(10-30)(11-36)(12-39)(13-34)(14-30)(15-31)(16-31)(17-42)(18-43)(19-55)(20-55)(21-41)(22-35)(23-30)(24-37)(25-45)(26-53)(27-40)(28-55)(29-52)(30-50)(31-52)(32-33)(32-50)(33-46)(34-44)(34-49)(35-40)(35-48)(36-51)(36-54)(37-38)(37-46)(38-50)(39-45)(39-49)(40-44)(41-42)(41-54)(42-43)(43-51)(45-47)(46-52)(47-53)(47-56)(48-49)(48-56)(51-57)(53-58)(54-58)(55-61)(56-59)(57-60)(57-61)(58-62)(61-62)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 7.1 | — | 10.1002/asia.202100917 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«Annexin V-PE/7-AAD double staining assay using two different dosages of 8 (5 and 7 μM) showed that there was ca. 11% and 18% apoptosis respectively, after treatment for 18 h. The percentage of the lat...»