Info
| ID | 2944 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 1, "O": 1} |
| Abbreviation | 7 |
| SMILES | COC(=O)c1cccc(/N=C/c2ccccc2[O-])c1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C25H26NO3Ru/(1-27)(2-30)(3-27)(4-31)(5-33)(6-32)(7-27)(8-28)(9-46)(10-29)(11-36)(12-28)(13-28)(14-47)(15-37)(16-38)(17-39)(18-49)(19-49)(20-41)(21-29)(22-29)(23-34)(24-40)(25-35)(26-49)(27-46)(28-46)(29-44)(30-31)(30-44)(31-43)(32-45)(32-48)(33-34)(33-44)(34-43)(35-40)(35-41)(36-40)(36-50)(37-38)(37-48)(38-39)(39-45)(41-42)(42-47)(42-50)(43-46)(45-51)(47-52)(48-52)(49-55)(50-53)(51-54)(51-55)(52-56)(55-56)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 10 | — | 10.1002/asia.202100917 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«Annexin V-PE/7-AAD double staining assay using two different dosages of 8 (5 and 7 μM) showed that there was ca. 11% and 18% apoptosis respectively, after treatment for 18 h. The percentage of the lat...»