Info
| ID | 2942 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3} |
| Abbreviation | 5 |
| SMILES | COC(=O)c1cccc(/N=C/c2ncc[nH]2)c1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C22H25N3O2Ru/(1-27)(2-31)(3-27)(4-30)(5-26)(6-40)(7-27)(8-33)(9-28)(10-28)(11-32)(12-26)(13-28)(14-43)(15-34)(16-35)(17-36)(18-46)(19-46)(20-42)(21-41)(22-26)(23-29)(24-46)(25-48)(26-38)(27-40)(28-40)(29-39)(29-44)(30-31)(30-37)(31-38)(32-33)(32-38)(33-37)(34-35)(34-44)(35-36)(36-39)(37-40)(39-47)(41-42)(41-48)(42-50)(43-45)(43-49)(44-49)(45-48)(45-50)(46-52)(47-51)(47-52)(49-53)(50-53)(52-53)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 2.5 | — | 10.1002/asia.202100917 | 2021 |
🧬 Cell Death Types (1)
Apoptosis
high
«Annexin V-PE/7-AAD double staining assay using two different dosages of 8 (5 and 7 μM) showed that there was ca. 11% and 18% apoptosis respectively, after treatment for 18 h. The percentage of the lat...»