Info
| ID | 2909 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 5 |
| SMILES | CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.[Cl-].c1ccccc1 |
TUCAN
C24H30N2Ru/(1-31)(2-31)(3-31)(4-44)(5-37)(6-38)(7-39)(8-40)(9-32)(10-46)(11-51)(12-52)(13-41)(14-42)(15-32)(16-43)(17-32)(18-33)(19-33)(20-33)(21-45)(22-34)(23-34)(24-34)(25-35)(26-35)(27-35)(28-36)(29-36)(30-36)(31-49)(32-49)(33-49)(34-50)(35-50)(36-50)(37-38)(37-39)(38-40)(39-41)(40-42)(41-42)(43-47)(43-51)(44-47)(44-53)(45-48)(45-52)(46-48)(46-54)(47-49)(48-50)(51-55)(52-56)(53-54)(53-55)(54-56)(55-57)(56-57)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| T24 | 30 | — | 10.3390/ijms241511896 | 2023 |
| MCF-10A | — | — | 10.3390/ijms241511896 | 2023 |
| Vero | — | — | 10.3390/ijms241511896 | 2023 |
| EA.hy926 | — | — | 10.3390/ijms241511896 | 2023 |
| HepG2 | — | — | 10.3390/ijms241511896 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«Fluorescence imaging and flow cytometry analysis demonstrate that 1 and 2 effectively penetrate the membrane and promote T24 cell death through the apoptotic pathway, mainly inducing early apoptosis o...»