Info
| ID | 2887 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 2 |
| SMILES | Cc1ccc2c(n1)c1nc(C)ccc1c1nc3ccccc3nc21.Cc1ccnc(-c2cc(C)ccn2)c1.Cc1ccnc(-c2cc(C)ccn2)c1 |
TUCAN
C44H38N8Ru/(1-45)(2-54)(3-46)(4-39)(5-67)(6-39)(7-68)(8-39)(9-40)(10-47)(11-42)(12-49)(13-42)(14-55)(15-53)(16-57)(17-40)(18-40)(19-41)(20-69)(21-41)(22-41)(23-42)(24-48)(25-60)(26-44)(27-51)(28-59)(29-58)(30-43)(31-70)(32-43)(33-43)(34-56)(35-52)(36-44)(37-50)(38-44)(39-61)(40-62)(41-63)(42-78)(43-65)(44-82)(45-61)(45-67)(46-61)(46-71)(47-62)(47-72)(48-51)(48-74)(49-55)(49-64)(50-52)(50-75)(51-52)(53-63)(53-73)(54-62)(54-68)(55-78)(56-65)(56-77)(57-63)(57-69)(58-65)(58-70)(59-60)(59-66)(60-82)(64-76)(64-79)(66-80)(66-81)(67-85)(68-86)(69-87)(70-90)(71-72)(71-85)(72-86)(73-77)(73-87)(74-75)(74-83)(75-84)(76-81)(76-83)(77-90)(78-88)(79-80)(79-88)(80-89)(81-84)(82-89)(85-91)(86-91)(87-91)(88-91)(89-91)(90-91)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| BEL-7402 | 17 | — | 10.1080/00958972.2011.640675 | 2012 |
| MCF-7 | 20 | — | 10.1080/00958972.2011.640675 | 2012 |
| MG-63 | 33 | — | 10.1080/00958972.2011.640675 | 2012 |
| HeLa | 37 | — | 10.1080/00958972.2011.640675 | 2012 |
🧬 Cell Death Types (1)
Apoptosis
high
«The results suggest that 1 and 2 can effectively induce the apoptosis of BEL-7402 cells.»