Info
| ID | 2886 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 1 |
| SMILES | Cc1ccc2c(n1)c1nc(C)ccc1c1nc3ccccc3nc21.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C40H30N8Ru/(1-31)(2-33)(3-55)(4-56)(5-31)(6-36)(7-35)(8-42)(9-41)(10-34)(11-43)(12-38)(13-37)(14-45)(15-57)(16-40)(17-39)(18-58)(19-31)(20-32)(21-44)(22-32)(23-46)(24-49)(25-51)(26-47)(27-52)(28-50)(29-32)(30-48)(31-63)(32-68)(33-34)(33-59)(34-35)(35-55)(36-38)(36-60)(37-38)(37-56)(39-40)(39-57)(40-47)(41-42)(41-53)(42-63)(43-45)(43-62)(44-48)(44-54)(45-46)(46-49)(47-65)(48-68)(49-66)(50-51)(50-58)(51-52)(52-67)(53-61)(53-69)(54-64)(54-70)(55-73)(56-74)(57-76)(58-77)(59-67)(59-73)(60-65)(60-74)(61-64)(61-75)(62-66)(62-71)(63-75)(64-78)(65-76)(66-72)(67-77)(68-78)(69-70)(69-71)(70-72)(73-79)(74-79)(75-79)(76-79)(77-79)(78-79)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 16 | — | 10.1080/00958972.2011.640675 | 2012 |
| HeLa | 21 | — | 10.1080/00958972.2011.640675 | 2012 |
| BEL-7402 | 33 | — | 10.1080/00958972.2011.640675 | 2012 |
| MG-63 | 35 | — | 10.1080/00958972.2011.640675 | 2012 |
🧬 Cell Death Types (1)
Apoptosis
high
«The results suggest that 1 and 2 can effectively induce the apoptosis of BEL-7402 cells.»