Info
| ID | 2721 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 2 |
| SMILES | Cc1ccc2ccc3ccc(C)nc3c2n1.Cc1ccc2ccc3ccc(C)nc3c2n1.O=C1c2ccccc2-c2nc3c4cccnc4c4ncccc4c3nc21 |
TUCAN
C49H34N8ORu/(1-35)(2-39)(3-68)(4-67)(5-42)(6-35)(7-35)(8-47)(9-36)(10-36)(11-36)(12-37)(13-56)(14-57)(15-43)(16-37)(17-54)(18-48)(19-45)(20-46)(21-55)(22-49)(23-37)(24-53)(25-41)(26-44)(27-50)(28-40)(29-38)(30-58)(31-52)(32-38)(33-38)(34-51)(35-72)(36-76)(37-78)(38-79)(39-42)(39-72)(40-41)(40-53)(41-48)(42-59)(43-45)(43-76)(44-46)(44-78)(45-60)(46-63)(47-49)(47-59)(48-61)(49-60)(50-58)(50-63)(51-52)(51-66)(52-79)(53-65)(54-55)(54-62)(55-67)(56-57)(56-64)(57-68)(58-66)(59-69)(60-74)(61-65)(61-83)(62-70)(62-75)(63-77)(64-73)(64-81)(65-80)(66-82)(67-84)(68-88)(69-74)(69-86)(70-73)(70-84)(71-80)(71-83)(71-85)(72-86)(73-88)(74-87)(75-81)(75-85)(76-87)(77-82)(77-89)(78-89)(79-91)(80-90)(81-90)(82-91)(83-92)(86-93)(87-93)(88-93)(89-93)(90-93)(91-93)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MG-63 | 15 | — | 10.1016/j.ica.2014.07.017 | 2014 |
| HeLa | 16 | — | 10.1016/j.ica.2014.07.017 | 2014 |
| A549 | 16 | — | 10.1016/j.ica.2014.07.017 | 2014 |
| HepG2 | 25 | — | 10.1016/j.ica.2014.07.017 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
high
«The complexes can effectively induce apoptosis in HeLa cells.»