Info
| ID | 2720 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 1 |
| SMILES | O=C1c2ccccc2-c2nc3c4cccnc4c4ncccc4c3nc21.c1cnc2c(c1)ccc1cccnc12.c1cnc2c(c1)ccc1cccnc12 |
TUCAN
C45H26N8ORu/(1-55)(2-36)(3-39)(4-45)(5-27)(6-28)(7-29)(8-30)(9-56)(10-40)(11-59)(12-37)(13-35)(14-33)(15-31)(16-32)(17-34)(18-41)(19-60)(20-44)(21-57)(22-46)(23-38)(24-58)(25-42)(26-43)(27-29)(27-55)(28-35)(28-56)(29-47)(30-37)(30-48)(31-32)(31-58)(32-49)(33-34)(33-54)(34-57)(35-50)(36-40)(36-47)(37-59)(38-39)(38-46)(39-45)(40-48)(41-44)(41-50)(42-43)(42-60)(43-51)(44-51)(45-53)(46-52)(47-61)(48-62)(49-64)(49-69)(50-63)(51-65)(52-53)(52-67)(53-71)(54-68)(54-70)(55-74)(56-75)(57-72)(58-79)(59-76)(60-77)(61-62)(61-74)(62-76)(63-65)(63-75)(64-70)(64-78)(65-77)(66-67)(66-71)(66-73)(67-78)(68-69)(68-72)(69-79)(70-73)(71-80)(74-81)(75-81)(76-81)(77-81)(78-81)(79-81)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 16 | — | 10.1016/j.ica.2014.07.017 | 2014 |
| HepG2 | 17 | — | 10.1016/j.ica.2014.07.017 | 2014 |
| MG-63 | 20 | — | 10.1016/j.ica.2014.07.017 | 2014 |
| HeLa | 25 | — | 10.1016/j.ica.2014.07.017 | 2014 |
🧬 Cell Death Types (1)
Apoptosis
high
«The complexes can effectively induce apoptosis in HeLa cells.»