Info
| ID | 2676 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | Δ-[Ru(bpy)2PBIP]2+ |
| SMILES | Brc1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C39H27BrN8Ru/(1-51)(2-39)(3-28)(4-52)(5-31)(6-29)(7-33)(8-34)(9-30)(10-32)(11-37)(12-47)(13-46)(14-38)(15-56)(16-53)(17-36)(18-35)(19-54)(20-40)(21-55)(22-45)(23-43)(24-44)(25-41)(26-42)(27-68)(28-31)(28-60)(29-31)(29-51)(30-35)(30-52)(32-43)(32-53)(33-35)(33-61)(34-38)(34-48)(36-43)(36-62)(37-39)(37-50)(38-56)(39-66)(40-47)(40-66)(41-44)(41-63)(42-44)(42-54)(45-46)(45-55)(46-49)(47-50)(48-59)(48-64)(49-57)(49-58)(50-65)(51-69)(52-70)(53-71)(54-73)(55-74)(56-67)(57-59)(57-72)(58-64)(58-74)(59-68)(60-61)(60-69)(61-70)(62-63)(62-71)(63-73)(64-67)(65-68)(65-72)(66-75)(69-76)(70-76)(71-76)(72-76)(73-76)(74-76)
Measurements (17)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| PC-3 | 2.8 | — | 10.1039/d3dt01584j | 2023 |
| PC-3 | 3.5 | — | 10.1039/d3dt01584j | 2023 |
| A2780 | 5.6 | — | 10.1039/d3dt01584j | 2023 |
| A2780 | 6.2 | — | 10.1039/d3dt01584j | 2023 |
| HeLa | 18 | — | 10.1039/d3dt01584j | 2023 |
| A375 | 21 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| HeLa | 27 | — | 10.1039/d3dt01584j | 2023 |
| Ect1/E6E7 | 39 | — | 10.1039/d3dt01584j | 2023 |
| BEAS-2B | 39 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| Ect1/E6E7 | 50 | — | 10.1039/d3dt01584j | 2023 |
| A375 | 73 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| HeLa | 1e+02 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| A549 | 1.4e+02 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| BEAS-2B | 1.4e+02 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| HeLa | 2e+02 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| A549 | 2.3e+02 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
| MCF-7 | 2.8e+02 | — | 10.1016/j.jinorgbio.2018.01.01... | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«Flow cytometry experiments showed that the apoptosis was enhanced by increasing the concentration of each enantiomer. Western blotting analyses indicated that both extrinsic and intrinsic apoptosis pa...»