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Complex #2667 — Ru(2) [Complex 3]

2D Structure

Structure
⬇ MOL V3000

Info

ID2667
MetalRu
Oxidation state2
Charge0
Donor atoms{"O": 1, "N": 3}
AbbreviationComplex 3
SMILESCc1ccc(C(C)C)cc1.[Cl-].[O-]/C(=N\N=C/c1cccs1)c1ccccn1

TUCAN

C21H22N3ORuS/(1-29)(2-28)(3-23)(4-34)(5-24)(6-23)(7-23)(8-33)(9-38)(10-27)(11-26)(12-31)(13-32)(14-39)(15-42)(16-24)(17-24)(18-25)(19-25)(20-37)(21-30)(22-25)(23-35)(24-37)(25-37)(26-27)(26-40)(27-33)(28-29)(28-35)(29-36)(30-34)(30-36)(31-32)(31-42)(32-43)(33-39)(34-35)(36-37)(38-43)(38-45)(39-44)(40-41)(40-44)(41-46)(41-47)(42-48)(43-48)(45-46)(45-49)(46-49)(48-49)

Measurements (4)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A5498.6 10.1039/d4dt01845a 2024
HuH-713 10.1039/d4dt01845a 2024
HeLa14 10.1039/d4dt01845a 2024
NIH-3T32.7e+02 10.1039/d4dt01845a 2024

🧬 Cell Death Types (1)

Apoptosis high
«flow cytometry analysis, utilizing dual staining of Annexin V-FITC and propidium iodide (PI), was employed to quantitatively study apoptosis induction»