Info
| ID | 2665 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | Complex 1 |
| SMILES | Cc1ccc(C(C)C)cc1.[Cl-].[O-]/C(=N\N=C/c1cccs1)c1ccco1 |
TUCAN
C20H21N2O2RuS/(1-23)(2-25)(3-26)(4-22)(5-22)(6-23)(7-22)(8-29)(9-40)(10-30)(11-31)(12-36)(13-37)(14-32)(15-23)(16-24)(17-35)(18-24)(19-27)(20-28)(21-24)(22-33)(23-35)(24-35)(25-26)(25-33)(26-34)(27-28)(27-34)(28-33)(29-32)(29-38)(30-31)(30-40)(31-41)(32-37)(34-35)(36-41)(36-42)(37-45)(38-39)(38-45)(39-43)(39-44)(40-46)(41-46)(42-43)(42-47)(43-47)(46-47)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 17 | — | 10.1039/d4dt01845a | 2024 |
| HeLa | 18 | — | 10.1039/d4dt01845a | 2024 |
| HuH-7 | 20 | — | 10.1039/d4dt01845a | 2024 |
| NIH-3T3 | 2.7e+02 | — | 10.1039/d4dt01845a | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«flow cytometry analysis, utilizing dual staining of Annexin V-FITC and propidium iodide (PI), was employed to quantitatively study apoptosis induction»