Info
| ID | 2625 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 3 |
| SMILES | COc1ccc(/C([O-])=C/N=C2/CCCc3c2[nH]c2ccccc32)cc1.[Cl-].c1ccccc1 |
TUCAN
C27H25N2O2Ru/(1-26)(2-27)(3-36)(4-40)(5-28)(6-29)(7-30)(8-33)(9-35)(10-34)(11-37)(12-31)(13-40)(14-41)(15-41)(16-42)(17-32)(18-42)(19-46)(20-38)(21-50)(22-50)(23-50)(24-39)(25-53)(26-27)(26-28)(27-29)(28-30)(29-31)(30-31)(32-37)(32-45)(33-34)(33-43)(34-35)(35-36)(36-49)(37-52)(38-39)(38-45)(39-52)(40-42)(40-44)(41-42)(41-47)(43-44)(43-49)(44-48)(45-51)(46-51)(46-54)(47-48)(47-54)(48-53)(49-53)(50-56)(51-55)(52-56)(54-57)(56-57)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 3 | — | 10.1039/d0dt01476a | 2020 |
| A2780 | 3 | — | 10.1039/d0dt01476a | 2020 |
| 16HBE | 93 | — | 10.1039/d0dt01476a | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«AO-EB fluorescent staining and flow cytometry analysis disclose that all the complexes induce cancer cell death by apoptosis mechanism.»