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Complex #2624 — Ru(2) [2]

2D Structure

Structure
⬇ MOL V3000

Info

ID2624
MetalRu
Oxidation state2
Charge0
Donor atoms{"O": 1, "N": 2}
Abbreviation2
SMILES[Cl-].[O-]/C(=C\N=C1\CCCc2c1[nH]c1ccccc21)c1ccc(Br)cc1.c1ccccc1

TUCAN

C26BrClN2ORu/(1-2)(1-3)(2-6)(3-9)(4-5)(4-26)(5-20)(6-16)(7-17)(7-22)(8-11)(8-12)(9-16)(10-15)(10-26)(11-23)(12-18)(13-14)(13-19)(14-17)(15-20)(18-19)(18-24)(19-22)(20-25)(21-25)(21-28)(22-27)(23-24)(23-28)(24-27)(25-29)(26-31)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A27806 10.1039/d0dt01476a 2020
A5497 10.1039/d0dt01476a 2020
16HBE88 10.1039/d0dt01476a 2020

🧬 Cell Death Types (1)

Apoptosis high
«AO-EB fluorescent staining and flow cytometry analysis disclose that all the complexes induce cancer cell death by apoptosis mechanism.»