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Complex #2623 — Ru(2) [1]

2D Structure

Structure
⬇ MOL V3000

Info

ID2623
MetalRu
Oxidation state2
Charge0
Donor atoms{"O": 1, "N": 2}
Abbreviation1
SMILES[Cl-].[O-]/C(=C\N=C1\CCCc2c1[nH]c1ccccc21)c1ccccc1.c1ccccc1

TUCAN

C26ClN2ORu/(1-2)(1-3)(2-4)(3-6)(4-10)(5-9)(5-11)(6-10)(7-11)(7-14)(8-12)(8-21)(9-19)(12-15)(13-17)(13-25)(14-19)(15-18)(16-17)(16-20)(18-24)(19-26)(20-21)(20-23)(21-24)(22-26)(22-28)(23-25)(23-27)(24-27)(25-28)(26-29)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A27808 10.1039/d0dt01476a 2020
A54910 10.1039/d0dt01476a 2020
16HBE66 10.1039/d0dt01476a 2020

🧬 Cell Death Types (1)

Apoptosis high
«AO-EB fluorescent staining and flow cytometry analysis disclose that all the complexes induce cancer cell death by apoptosis mechanism.»