Info
| ID | 2621 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"O": 1, "N": 2, "S": 1, "P": 4} |
| Abbreviation | 5 |
| SMILES | O=[N+]([O-])c1ccc2[nH]c([S-])nc2c1.c1ccc(P(CP(c2ccccc2)c2ccccc2)c2ccccc2)cc1.c1ccc(P(CP(c2ccccc2)c2ccccc2)c2ccccc2)cc1 |
TUCAN
C57H48N3O2P4RuS/(1-49)(2-53)(3-50)(4-57)(5-56)(6-59)(7-51)(8-60)(9-103)(10-62)(11-63)(12-52)(13-54)(14-55)(15-65)(16-58)(17-61)(18-68)(19-73)(20-64)(21-70)(22-66)(23-69)(24-78)(25-89)(26-74)(27-72)(28-103)(29-80)(30-75)(31-76)(32-77)(33-81)(34-85)(35-90)(36-82)(37-83)(38-104)(39-79)(40-104)(41-87)(42-84)(43-86)(44-88)(45-91)(46-71)(47-67)(48-106)(49-50)(49-57)(50-95)(51-53)(51-95)(52-56)(52-96)(53-57)(54-59)(54-96)(55-62)(55-97)(56-60)(58-63)(58-97)(59-60)(61-65)(61-98)(62-70)(63-70)(64-68)(64-98)(65-74)(66-73)(66-99)(67-71)(67-92)(68-74)(69-78)(69-99)(71-93)(72-80)(72-100)(73-76)(75-82)(75-100)(76-78)(77-83)(77-101)(79-80)(79-82)(81-84)(81-101)(83-87)(84-87)(85-86)(85-102)(86-91)(88-90)(88-91)(89-93)(89-94)(90-102)(92-94)(92-106)(93-107)(94-108)(95-111)(96-111)(97-112)(98-112)(99-113)(100-113)(101-114)(102-114)(103-111)(103-112)(104-113)(104-114)(105-106)(105-108)(105-115)(107-109)(107-110)(108-116)(111-116)(112-116)(113-116)(114-116)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| CT-26 | 6.3 | — | 10.1002/cbic.202400734 | 2025 |
| RPE-1 | 8.8 | — | 10.1002/cbic.202400734 | 2025 |
| HT-29 | 11 | — | 10.1002/cbic.202400734 | 2025 |
| A549 | 11 | — | 10.1002/cbic.202400734 | 2025 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.