Info
| ID | 2563 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | 2 |
| SMILES | Cc1ccnc(-c2cc(C)ccn2)c1.Cc1ccnc(-c2cc(C)ccn2)c1.Nc1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)c(N)c1 |
TUCAN
C43H38N10Ru/(1-39)(2-66)(3-39)(4-47)(5-48)(6-67)(7-39)(8-49)(9-40)(10-51)(11-40)(12-43)(13-68)(14-40)(15-50)(16-56)(17-53)(18-54)(19-70)(20-46)(21-44)(22-45)(23-57)(24-41)(25-69)(26-55)(27-41)(28-65)(29-52)(30-41)(31-42)(32-42)(33-42)(34-82)(35-83)(36-85)(37-82)(38-83)(39-59)(40-60)(41-63)(42-64)(43-51)(43-65)(44-75)(44-77)(45-46)(45-77)(46-62)(47-59)(47-66)(48-59)(48-72)(49-60)(49-73)(50-60)(50-67)(51-61)(52-53)(52-69)(53-58)(54-63)(54-74)(55-64)(55-78)(56-63)(56-68)(57-64)(57-70)(58-71)(58-79)(61-76)(61-80)(62-75)(62-81)(65-84)(66-87)(67-88)(68-89)(69-90)(70-91)(71-80)(71-86)(72-73)(72-87)(73-88)(74-78)(74-89)(75-82)(76-79)(76-84)(77-83)(78-91)(79-90)(80-85)(81-85)(81-86)(86-92)(87-92)(88-92)(89-92)(90-92)(91-92)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 78 | — | 10.1080/00958972.2012.713945 | 2013 |
| HepG2 | 88 | — | 10.1080/00958972.2012.713945 | 2013 |
| BEL-7402 | — | — | 10.1080/00958972.2012.713945 | 2013 |
🧬 Cell Death Types (1)
Apoptosis
high
«The results show 2 can effectively induce apoptosis.»