Info
| ID | 2562 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 4, "O": 1} |
| Abbreviation | 1 |
| SMILES | Cc1ccnc(-c2cc(C)ccn2)c1.Cc1ccnc(-c2cc(C)ccn2)c1.O=[N+]([O-])c1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)c([N+](=O)[O-])c1 |
TUCAN
C43H34N10O4Ru/(1-35)(2-62)(3-61)(4-43)(5-41)(6-49)(7-51)(8-63)(9-35)(10-53)(11-64)(12-44)(13-35)(14-40)(15-50)(16-42)(17-65)(18-36)(19-47)(20-52)(21-45)(22-46)(23-36)(24-36)(25-66)(26-37)(27-37)(28-39)(29-48)(30-37)(31-38)(32-38)(33-38)(34-80)(35-55)(36-56)(37-58)(38-60)(39-50)(39-68)(40-55)(40-61)(41-44)(41-62)(42-58)(42-63)(43-55)(43-69)(44-57)(45-46)(45-54)(46-66)(47-56)(47-64)(48-68)(48-73)(49-56)(49-70)(50-59)(51-58)(51-71)(52-60)(52-65)(53-60)(53-72)(54-67)(54-76)(57-74)(57-75)(59-73)(59-77)(61-83)(62-79)(63-84)(64-86)(65-87)(66-78)(67-74)(67-80)(68-81)(69-70)(69-83)(70-86)(71-72)(71-84)(72-87)(73-82)(74-85)(75-76)(75-79)(76-78)(77-80)(77-85)(81-88)(81-91)(82-89)(82-90)(83-92)(84-92)(85-92)(86-92)(87-92)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 51 | — | 10.1080/00958972.2012.713945 | 2013 |
| BEL-7402 | 60 | — | 10.1080/00958972.2012.713945 | 2013 |
| MCF-7 | 70 | — | 10.1080/00958972.2012.713945 | 2013 |
🧬 Cell Death Types (1)
Apoptosis
high
«The results show 2 can effectively induce apoptosis.»