Info
| ID | 2514 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 7 |
| SMILES | CN(C)/C=C/c1ccnc(-c2cc(/C=C/N(C)C)ccn2)c1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1 |
TUCAN
C66H54N8Ru/(1-57)(2-60)(3-55)(4-58)(5-59)(6-66)(7-56)(8-61)(9-62)(10-63)(11-73)(12-111)(13-74)(14-103)(15-103)(16-103)(17-85)(18-104)(19-104)(20-104)(21-105)(22-105)(23-105)(24-110)(25-106)(26-86)(27-65)(28-71)(29-77)(30-79)(31-68)(32-70)(33-67)(34-84)(35-64)(36-80)(37-76)(38-82)(39-69)(40-83)(41-88)(42-106)(43-106)(44-112)(45-107)(46-108)(47-75)(48-81)(49-109)(50-72)(51-78)(52-113)(53-87)(54-114)(55-56)(55-89)(56-57)(57-61)(58-61)(58-89)(59-91)(59-107)(60-62)(60-63)(62-66)(63-68)(64-71)(64-77)(65-92)(65-108)(66-90)(67-69)(67-94)(68-90)(69-95)(70-71)(70-93)(72-97)(72-109)(73-101)(73-116)(74-101)(74-111)(75-81)(75-96)(76-79)(76-84)(77-80)(78-99)(78-113)(79-82)(80-93)(81-98)(82-100)(83-84)(83-100)(85-102)(85-118)(86-101)(86-110)(87-102)(87-114)(88-102)(88-112)(89-91)(90-92)(91-94)(92-95)(93-97)(94-115)(95-117)(96-97)(96-119)(98-99)(98-120)(99-100)(103-121)(104-121)(105-122)(106-122)(107-123)(108-124)(109-126)(110-121)(111-125)(112-128)(113-127)(114-122)(115-117)(115-123)(116-118)(116-125)(117-124)(118-128)(119-120)(119-126)(120-127)(123-129)(124-129)(125-129)(126-129)(127-129)(128-129)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| CT-26 | 94 | 6.6 | 10.1021/jacs.9b13620 | 2020 |
| U-87 MG | — | 7.9 | 10.1021/jacs.9b13620 | 2020 |
| U373 | — | 15 | 10.1021/jacs.9b13620 | 2020 |
| HeLa | — | 15 | 10.1021/jacs.9b13620 | 2020 |
| RPE-1 | — | 8.9 | 10.1021/jacs.9b13620 | 2020 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.