Info
| ID | 2441 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 4, "O": 1} |
| Abbreviation | 4 |
| SMILES | [N-]=[N+]=[N-].[O-]C(=NN=Cc1ccc2ccc3cccc4ccc1c2c34)c1cccs1.c1ccccc1 |
TUCAN
C28H19N5ORuS/(1-20)(2-21)(3-22)(4-23)(5-26)(6-32)(7-30)(8-36)(9-44)(10-28)(11-35)(12-31)(13-29)(14-25)(15-46)(16-24)(17-33)(18-34)(19-27)(20-21)(20-22)(21-23)(22-26)(23-27)(24-25)(24-46)(25-47)(26-27)(28-33)(28-40)(29-32)(29-39)(30-31)(30-39)(31-38)(32-37)(33-34)(34-37)(35-36)(35-40)(36-42)(37-41)(38-42)(38-44)(39-43)(40-41)(41-43)(42-43)(44-50)(45-47)(45-51)(45-53)(46-54)(47-54)(48-52)(49-52)(50-51)(50-55)(51-55)(52-55)(54-55)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A431 | 14 | — | 10.1039/d1dt04093f | 2022 |
| MCF-7 | 16 | — | 10.1039/d1dt04093f | 2022 |
| HeLa | 20 | — | 10.1039/d1dt04093f | 2022 |
| HEK293 | 50 | — | 10.1039/d1dt04093f | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The Hoechst/PI dual staining method confirmed the apoptosis mode of cell death.»