Info
| ID | 2440 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 4, "O": 1} |
| Abbreviation | 3 |
| SMILES | Cc1ccc(C(C)C)cc1.[N-]=[N+]=[N-].[O-]C(=NN=Cc1ccc2ccc3cccc4ccc1c2c34)c1cccs1 |
TUCAN
C32H27N5ORuS/(1-37)(2-28)(3-29)(4-29)(5-28)(6-31)(7-41)(8-32)(9-42)(10-36)(11-43)(12-44)(13-38)(14-56)(15-40)(16-39)(17-58)(18-29)(19-30)(20-55)(21-34)(22-28)(23-33)(24-30)(25-30)(26-45)(27-35)(28-48)(29-55)(30-55)(31-32)(31-50)(32-40)(33-34)(33-48)(34-49)(35-45)(35-49)(36-39)(36-52)(37-38)(37-47)(38-52)(39-51)(40-51)(41-42)(41-59)(42-58)(43-44)(43-46)(44-50)(45-48)(46-47)(46-53)(47-56)(49-55)(50-54)(51-54)(52-53)(53-54)(56-63)(57-59)(57-62)(57-65)(58-66)(59-66)(60-64)(61-64)(62-63)(62-67)(63-67)(64-67)(66-67)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A431 | 8.4 | — | 10.1039/d1dt04093f | 2022 |
| HeLa | 11 | — | 10.1039/d1dt04093f | 2022 |
| MCF-7 | 15 | — | 10.1039/d1dt04093f | 2022 |
| HEK293 | 49 | — | 10.1039/d1dt04093f | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The Hoechst/PI dual staining method confirmed the apoptosis mode of cell death.»