home← all complexes D-MPNN

Complex #2440 — Ru(2) [3]

2D Structure

Structure
⬇ MOL V3000

Info

ID2440
MetalRu
Oxidation state2
Charge0
Donor atoms{"N": 4, "O": 1}
Abbreviation3
SMILESCc1ccc(C(C)C)cc1.[N-]=[N+]=[N-].[O-]C(=NN=Cc1ccc2ccc3cccc4ccc1c2c34)c1cccs1

TUCAN

C32H27N5ORuS/(1-37)(2-28)(3-29)(4-29)(5-28)(6-31)(7-41)(8-32)(9-42)(10-36)(11-43)(12-44)(13-38)(14-56)(15-40)(16-39)(17-58)(18-29)(19-30)(20-55)(21-34)(22-28)(23-33)(24-30)(25-30)(26-45)(27-35)(28-48)(29-55)(30-55)(31-32)(31-50)(32-40)(33-34)(33-48)(34-49)(35-45)(35-49)(36-39)(36-52)(37-38)(37-47)(38-52)(39-51)(40-51)(41-42)(41-59)(42-58)(43-44)(43-46)(44-50)(45-48)(46-47)(46-53)(47-56)(49-55)(50-54)(51-54)(52-53)(53-54)(56-63)(57-59)(57-62)(57-65)(58-66)(59-66)(60-64)(61-64)(62-63)(62-67)(63-67)(64-67)(66-67)

Measurements (4)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A4318.4 10.1039/d1dt04093f 2022
HeLa11 10.1039/d1dt04093f 2022
MCF-715 10.1039/d1dt04093f 2022
HEK29349 10.1039/d1dt04093f 2022

🧬 Cell Death Types (1)

Apoptosis high
«The Hoechst/PI dual staining method confirmed the apoptosis mode of cell death.»