Info
| ID | 2439 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 2} |
| Abbreviation | 2 |
| SMILES | [Cl-].[O-]C(=NN=Cc1ccc2ccc3cccc4ccc1c2c34)c1cccs1.c1ccccc1 |
TUCAN
C28H19N2ORuS/(1-20)(2-21)(3-22)(4-27)(5-28)(6-46)(7-30)(8-31)(9-36)(10-44)(11-32)(12-35)(13-29)(14-33)(15-23)(16-26)(17-34)(18-24)(19-25)(20-21)(20-22)(21-23)(22-24)(23-25)(24-25)(26-34)(26-40)(27-33)(27-39)(28-33)(28-38)(29-30)(29-38)(30-37)(31-32)(31-37)(32-43)(34-39)(35-36)(35-46)(36-47)(37-41)(38-42)(39-42)(40-41)(40-43)(41-42)(43-44)(44-49)(45-47)(45-48)(45-50)(46-51)(47-51)(48-49)(48-52)(49-52)(51-52)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MCF-7 | 7.3 | — | 10.1039/d1dt04093f | 2022 |
| HEK293 | 43 | — | 10.1039/d1dt04093f | 2022 |
| HeLa | — | — | 10.1039/d1dt04093f | 2022 |
| A431 | — | — | 10.1039/d1dt04093f | 2022 |
🧬 Cell Death Types (1)
Apoptosis
high
«The Hoechst/PI dual staining method confirmed the apoptosis mode of cell death.»