Info
| ID | 2419 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1} |
| Abbreviation | 1 |
| SMILES | COc1ccc(C(=O)/C=C(\[O-])c2ccc(C(C)(C)C)cc2)cc1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C30ClO3Ru/(1-26)(2-23)(3-20)(4-26)(5-20)(6-26)(7-8)(7-23)(8-22)(9-19)(9-22)(10-12)(10-28)(11-15)(11-24)(12-25)(13-14)(13-25)(14-28)(15-21)(16-29)(16-30)(17-18)(17-24)(18-21)(19-23)(20-22)(21-26)(24-29)(25-30)(27-33)(28-33)(29-31)(30-32)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| NIH-3T3 | 3 | — | 10.1016/j.jinorgbio.2018.08.00... | 2018 |
| HeLa | 3 | — | 10.1016/j.jinorgbio.2018.08.00... | 2018 |
| A549 | 4 | — | 10.1016/j.jinorgbio.2018.08.00... | 2018 |
| MCF-7 | 4 | — | 10.1016/j.jinorgbio.2018.08.00... | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«These results confirmed that both complexes induced cytotoxicity followed by apoptosis in the cancer cell lines through subG1 phase arrest. ... From the apoptosis assays, it was clear that 5 μM of com...»