Info
| ID | 2299 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | 1 |
| SMILES | Oc1c(Br)cc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1Br.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C39H26Br2N8ORu/(1-28)(2-48)(3-27)(4-51)(5-30)(6-29)(7-32)(8-35)(9-53)(10-49)(11-50)(12-33)(13-41)(14-34)(15-38)(16-31)(17-39)(18-43)(19-36)(20-52)(21-44)(22-37)(23-42)(24-40)(25-67)(26-74)(27-28)(27-29)(28-48)(29-54)(30-38)(30-42)(31-32)(31-39)(32-49)(33-41)(33-53)(34-45)(34-64)(35-44)(35-51)(36-45)(36-65)(37-40)(37-50)(38-55)(39-56)(40-43)(41-46)(42-52)(43-60)(44-47)(45-62)(46-58)(46-61)(47-57)(47-59)(48-68)(49-69)(50-70)(51-66)(52-71)(53-72)(54-55)(54-68)(55-71)(56-60)(56-69)(57-58)(57-66)(58-72)(59-61)(59-67)(60-70)(61-73)(62-67)(62-73)(63-64)(63-65)(63-74)(64-75)(65-76)(68-77)(69-77)(70-77)(71-77)(72-77)(73-77)(74-77)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| BEL-7402 | 41 | — | 10.1016/j.ejmech.2010.03.042 | 2010 |
| BEL-7402 | 56 | — | 10.1016/j.ejmech.2010.03.042 | 2010 |
| C6 | — | — | 10.1016/j.ejmech.2010.03.042 | 2010 |
| HepG2 | — | — | 10.1016/j.ejmech.2010.03.042 | 2010 |
| MCF-7 | — | — | 10.1016/j.ejmech.2010.03.042 | 2010 |
🧬 Cell Death Types (1)
Apoptosis
high
«Cytotoxicity evaluation in vitro shows that the ligand and its complex 2 all displayed antitumor activity against the selected tumor cell lines and complexes 1 and 2 can induce the apoptosis of BEL-74...»