Info
| ID | 2294 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 2} |
| Abbreviation | 4 |
| SMILES | Cc1ccncc1.c1cc[cH-]c1.c1ccc(P(CCP(c2ccccc2)c2ccccc2)c2ccccc2)cc1 |
TUCAN
C37H36NP2Ru/(1-42)(2-68)(3-40)(4-43)(5-38)(6-45)(7-58)(8-59)(9-37)(10-41)(11-46)(12-48)(13-50)(14-47)(15-51)(16-53)(17-52)(18-56)(19-68)(20-63)(21-69)(22-69)(23-49)(24-54)(25-55)(26-57)(27-60)(28-66)(29-61)(30-37)(31-62)(32-39)(33-37)(34-67)(35-64)(36-44)(37-65)(38-40)(38-42)(39-65)(39-66)(40-41)(41-43)(42-70)(43-70)(44-65)(44-67)(45-48)(45-71)(46-50)(46-71)(47-51)(47-72)(48-49)(49-50)(51-54)(52-53)(52-54)(53-72)(55-56)(55-60)(56-73)(57-60)(57-63)(58-59)(58-61)(59-62)(61-64)(62-64)(63-73)(66-74)(67-74)(68-69)(68-75)(69-76)(70-75)(71-75)(72-76)(73-76)(74-77)(75-77)(76-77)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HL60 | 0.92 | — | 10.1016/j.jinorgbio.2010.10.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«All ruthenium complexes induce cell death mainly by apoptosis.»