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Complex #2293 — Ru(2) [3]

2D Structure

Structure
⬇ MOL V3000

Info

ID2293
MetalRu
Oxidation state2
Charge1
Donor atoms{"N": 1, "P": 2}
Abbreviation3
SMILESCc1ccncc1.c1cc[cH-]c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

TUCAN

C47H42NP2Ru/(1-48)(2-46)(3-49)(4-44)(5-45)(6-50)(7-52)(8-63)(9-54)(10-43)(11-64)(12-55)(13-53)(14-58)(15-70)(16-71)(17-59)(18-60)(19-56)(20-65)(21-47)(22-74)(23-82)(24-75)(25-77)(26-83)(27-78)(28-57)(29-61)(30-62)(31-68)(32-66)(33-67)(34-69)(35-72)(36-76)(37-79)(38-73)(39-51)(40-80)(41-43)(42-43)(43-81)(44-46)(44-48)(45-46)(45-49)(47-81)(47-82)(48-84)(49-84)(50-52)(50-85)(51-81)(51-83)(52-63)(53-54)(53-63)(54-85)(55-58)(55-86)(56-59)(56-86)(57-60)(57-87)(58-64)(59-64)(60-70)(61-65)(61-87)(62-66)(62-88)(65-70)(66-71)(67-68)(67-71)(68-88)(69-72)(69-89)(72-79)(73-76)(73-79)(74-75)(74-77)(75-78)(76-89)(77-80)(78-80)(82-90)(83-90)(84-91)(85-91)(86-91)(87-92)(88-92)(89-92)(90-93)(91-93)(92-93)

Measurements (1)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HL601.1 10.1016/j.jinorgbio.2010.10.00... 2011

🧬 Cell Death Types (1)

Apoptosis high
«All ruthenium complexes induce cell death mainly by apoptosis.»