Info
| ID | 2292 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2, "P": 2} |
| Abbreviation | 2 |
| SMILES | c1cc[cH-]c1.c1ccc(-c2ccccn2)nc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C51H43N2P2Ru/(1-47)(2-48)(3-44)(4-46)(5-54)(6-60)(7-45)(8-55)(9-57)(10-85)(11-67)(12-56)(13-63)(14-61)(15-64)(16-65)(17-70)(18-58)(19-59)(20-72)(21-62)(22-66)(23-81)(24-84)(25-49)(26-50)(27-80)(28-73)(29-68)(30-71)(31-74)(32-75)(33-69)(34-77)(35-76)(36-83)(37-78)(38-79)(39-82)(40-51)(41-52)(42-53)(43-86)(44-47)(44-89)(45-48)(45-89)(46-47)(46-48)(49-50)(49-51)(50-52)(51-53)(52-53)(54-55)(54-61)(55-90)(56-57)(56-87)(57-67)(58-60)(58-90)(59-63)(59-91)(60-61)(62-65)(62-91)(63-64)(64-65)(66-70)(66-92)(67-85)(68-72)(68-92)(69-70)(69-72)(71-73)(71-93)(73-77)(74-75)(74-93)(75-77)(76-78)(76-83)(78-94)(79-82)(79-94)(80-81)(80-84)(81-88)(82-83)(84-86)(85-95)(86-96)(87-88)(87-95)(88-96)(89-97)(90-97)(91-97)(92-98)(93-98)(94-98)(95-99)(96-99)(97-99)(98-99)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HL60 | 0.42 | — | 10.1016/j.jinorgbio.2010.10.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«All ruthenium complexes induce cell death mainly by apoptosis.»