Info
| ID | 2291 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2, "P": 2} |
| Abbreviation | 1 |
| SMILES | C1=NCCN1Cc1ccccc1.c1cc[cH-]c1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C51H47N2P2Ru/(1-49)(2-48)(3-50)(4-51)(5-52)(6-54)(7-53)(8-55)(9-61)(10-91)(11-92)(12-60)(13-68)(14-62)(15-63)(16-66)(17-58)(18-59)(19-67)(20-72)(21-74)(22-77)(23-85)(24-64)(25-65)(26-71)(27-75)(28-70)(29-76)(30-82)(31-69)(32-78)(33-84)(34-83)(35-80)(36-81)(37-86)(38-56)(39-57)(40-89)(41-90)(42-73)(43-79)(44-90)(45-91)(46-87)(47-89)(48-49)(48-93)(49-53)(50-52)(50-93)(51-54)(51-94)(52-53)(54-60)(55-61)(55-94)(56-57)(56-73)(57-79)(58-62)(58-95)(59-63)(59-95)(60-61)(62-68)(63-68)(64-66)(64-96)(65-67)(65-96)(66-69)(67-69)(70-71)(70-78)(71-97)(72-74)(72-88)(73-87)(74-77)(75-76)(75-97)(76-78)(77-85)(79-87)(80-82)(80-98)(81-84)(81-98)(82-83)(83-84)(85-86)(86-88)(88-89)(89-99)(90-91)(90-99)(91-100)(92-99)(92-100)(93-101)(94-101)(95-101)(96-102)(97-102)(98-102)(100-103)(101-103)(102-103)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HL60 | 0.38 | — | 10.1016/j.jinorgbio.2010.10.00... | 2011 |
🧬 Cell Death Types (1)
Apoptosis
high
«All ruthenium complexes induce cell death mainly by apoptosis.»