Info
| ID | 2195 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 3, "P": 1} |
| Abbreviation | 6 |
| SMILES | [Cl-].c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1.c1ccc(Nc2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
TUCAN
C54H42N3PRu/(1-46)(2-48)(3-50)(4-47)(5-45)(6-44)(7-64)(8-62)(9-71)(10-49)(11-43)(12-58)(13-67)(14-60)(15-56)(16-88)(17-54)(18-61)(19-51)(20-66)(21-52)(22-57)(23-59)(24-89)(25-75)(26-68)(27-55)(28-70)(29-73)(30-74)(31-63)(32-65)(33-72)(34-69)(35-53)(36-77)(37-76)(38-78)(39-79)(40-80)(41-81)(42-97)(43-44)(43-52)(44-92)(45-47)(45-49)(46-47)(46-94)(48-49)(48-94)(50-51)(50-95)(51-61)(52-54)(53-55)(53-63)(54-64)(55-65)(56-58)(56-60)(57-68)(57-82)(58-83)(59-60)(59-67)(61-66)(62-66)(62-95)(63-69)(64-92)(65-93)(67-83)(68-85)(69-93)(70-73)(70-74)(71-73)(71-96)(72-74)(72-96)(75-86)(75-88)(76-78)(76-80)(77-87)(77-89)(78-79)(79-81)(80-84)(81-84)(82-86)(82-90)(83-86)(84-87)(85-87)(85-91)(88-98)(89-99)(90-91)(90-98)(91-99)(92-97)(93-97)(94-100)(95-100)(96-100)(98-101)(99-101)(100-101)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 1.6 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
| V79 | 3.1 | — | 10.1016/j.jinorgbio.2019.01.00... | 2019 |
🧬 Cell Death Types (1)
Apoptosis
medium
«There were more round cells, when compared to the control cells, which is indicative of cell detachment, probably due to apoptotic cell death.»